Ancient Wisdom, New Technology
Cannabimimetics are naturally occurring chemicals found in plants, herbs, spices, and seeds, such as black pepper, sage, basil and lavender that stimulate the Endocannabinoid System (ECS).
The discovery of the ECS has led to the recognition of a vast network of cellular receptors within the body whose sole responsibility is maintaining optimal health and homeostasis, including regulation of sleep, appetite, immune function, mood and pain.
EndoTEAS uses proprietary blends of cannabimimetic herbs, spices, fruits, nuts, seeds and oils to support the ECS without the use of cannabis or hemp.
What are they and What they mean for Mammals
Our focus at Cannabimimetics.org is to research and create delicious superfood recipes with cannabimimetics ingredients. Cannabimimetics are botanicals that possess the same chemical compounds as those found in cannabis sativa and or cannabis indica, and specifically bind the endocannabinoid system CB1 Receptors.
The plant kingdom has thousands of terpenes. There are dictionaries and encyclopedias for the myriad terpene categories. For our purposes here, we are focusing on the primary and secondary cannabimimetic terpenes and their nutritional and health benefits. These are listed below.
For example, black pepper and cannabis sativa both possess the a-caryophyllene terpene with anti-anxiety health benefits. Both cannabis sativa, cannabis indica and rosemary possess the pinene terpene with sedative health properties. Both the a- caryophyllene and the pinene terpenes effect the endocannabinoid system CB1 Receptors. Therefore, black pepper and rosemary are considered cannabimimetics!
There are two endocannabinoid system (ECS) receptors, CB1 and CB2. ECS CB1 Receptors are primarily located throughout our brain. ECS CB2 Receptors are primarily located throughout our body. CB1 and CB2 Receptors overlap in many ECS designated locations throughout the brain and body. For ECS and its CB1 and CB2 Receptors diagrams and more information, please click here or go to Activate your ECS Page above.
Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation?
Cannabinoid receptors in humans evolved with their diet, and the ECS constitutes a feedback loop for food selection and energy metabolism.
Here, it is postulated that the mismatch of ancient lipid genes of hunter-gatherers and pastoralists with the high-carbohydrate diet introduced by agriculture could be compensated for via dietary modulation of the ECS.
Dietary secondary metabolites from vegetables and spices able to enhance the activity of cannabinoid-type 2 (CB2 ) receptors may provide adaptive metabolic advantages and counteract inflammation.
Food able to modulate the CB1 /CB2 receptor activation ratio may thus play a role in the nutrition transition of Western high-calorie diets.
The emerging potential of cannabimimetic food as a nutraceutical strategy is critically discussed.
Terpenes and their health benefits we synergize in our products:
Bisabolol anti anxiety, antibacterial, anti inflammatory, analgesic, sedative
Borneol - combats fatigue, anti-inflammatory, anti-nociceptive, anti inflammatory, antispasmodic, gastrointestinal aid, sedative
Camphene anti inflammatory, antispasmodic, gastrointestinal aid, sedative, antioxidant effects
Camphor slight local anesthetic and an antimicrobial substance
β Caryophyllene analgesic, anti anxiety, antidepressant, anti inflammatory, antioxidant, gastrointestinal aid, addiction recovery aid - Binds CB2 Receptors, produces anti-inflammatory and analgesic effects.
Citronellol - anti inflammatory, antispasmodic, gastrointestinal aid, sedative
Cymene possesses anti-inflammatory effects
Echinacoside - Binds CB2 Receptors
Eucalyptol - neuroprotectant,
Eugenol - analgesic, anti anxiety, antibacterial, antifungal, anti inflammatory
Flavonoids - anti anxiety, anti depressant, anti inflammatory, antioxidant, antitumorigenic, antiviral, neuroprotectant
Fenchol exhibits antibacterial properties.
Geraniol - antioxidant, neuroprotectant
Geranyl Acetate possesses antimicrobial effects
Honokiol - anti inflammatory, antispasmodic, gastrointestinal aid, sedative - Binds CB1 Receptors
Humulene - appetite suppressant, anti-inflammatory, analgesic, anti anxiety, antibacterial, anti depressant, anti inflammatory
Inulin - analgesic, antiseptic
Isoborneol possesses antiviral properties
Limonene - analgesic, anti anxiety, antibacterial, antifungal, anti inflammatory, depression.
Linalool sedative properties, anti anxiety analgesic, anti-epileptic
Magnolol - Binds CB1 Receptors
Methytican - Binds CB1 Receptors
Myrcene - analgesic, anti anxiety, sedative
Ocimene possess antifungal properties.
α Pinene - gastrointestinal, neuroprotectant, ace inhibitor, anti-inflammatory, anti bronchodilator
Phenolic compounds - antidiabetic, antioxidants, antitumorigenic, antiviral, neuroprotectant, chronic obesity aid
Phytol inhibits the enzyme that degrades the neurotransmitter GABA
Sabinene shown to benefit liver function and digestion, relieve arthritis and soothe skin conditions.
Tannin - antispasmodic, expectorant, sedative
Terpineol is a sedative
Terpinolene possesses antioxidant, sedative and anticancer effects in rat brain cells
Thujone - antiemetic
Valencene - relaxant. anti anxiety
Yangonin - Binds CB1 Receptors